Center for Catalytic Hydrocarbon Functionalizations

Institute for Basic Science (IBS) & Korea Advanced Institute of Science and Technology (KAIST)

Center for Catalytic Hydrocarbon Functionalizations

Professor Chang's group studies new organic reactions and mechanisms with transition metal catalysis. Research topics in our group have ranged in the development of new useful synthetic methodologies based on transition metal chemistry, synthesis of biologically important products, organic catalysis, chirality amplification and molecular mechanics based on molecular assembly. Research goals include transition metal catalyzed C–H bond functionalization for the carbon–carbon bond and carbon–heteroatom bond formation, development of useful catalytic organic transformations, methane activation and catalytic de-functionalization.

(04/08/2023) Hoonchul's paper entitled "Mechanistic Approach Toward the C4-Selective Amination of Pyridines via Nucleophilic Substitution of Hydrogen" is now accepted for publication at Angewandte Chemie International Edition! Congratulations to Hoonchul, Won Seok, Pit, Jianbo and Dongwook Kim!

(04/05/2024) We threw our annual Strawberry Party with other groups from Center for Catalytic Hydrocarbon Functionalizations! It was the perfect weather for picnic under beautifully bloomed cherry blossom. 

Hyeyun's work on Ni/photoredox amidative β-scission of alcohols is accepted for publication in JACS!

(12/06/2023) Hyeyun's paper entitled "Amidative β-Scission of Alcohols Enabled by Dual Catalysis of Photoredox Proton-Coupled Electron Transfer and Inner-Sphere Ni-Nitrenoid Transfer" is now accepted for publication at JACS! Congratulations to Hyeyun, Harin, and Dongwook!

(11/30/2023) Sourav and Jeonguk's paper entitled "A Formal γ-C–H Functionalization of Carboxylic Acids Guided by Metal-Nitrenoids as an Unprecedented Mechanistic Motif" is now accepted for publication at JACS! Congratulations to Sourav, Jeonguk, Manoj, Hoimin, Joon, Yeong Bum, Dongwook, and Jung-Woo!

(11/05/2023) Euijae's paper entitled "Iridium Acylnitrenoid-Initiated Biomimetic Cascade Cyclizations: Stereodefined Access to Polycyclic δ-Lactams" is now online at JACS! A huge collaboration with Prof. Giuseppe Zanoni's group (University of Pavia). Congratulations to Euijae, Hoimin, Jihye, and Dongwook!

(10/31/2023) Qing's paper entitled "Iridium-Catalyzed Migratory Terminal C(sp³)–H Amidation of Heteroatom-Substituted Internal Alkenes via Olefin Chain Walking" is now published at JACS! Congratulations to Qing, Hoimin and Dongwook!